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Sigma
Antimycin A from Streptomyces sp.
A8674
DOWNLOAD MSDS (PDF)CAS Number: 1397-94-0
MDL number: MFCD01779723
PubChem Substance ID: 24891355
Properties
| Related Categories | AN-AZ, Antibiotics, Antibiotics A to Z, Antibiotics A-F, Antibiotics by Application, |
| Quality Level | PREMIUM |
| storage temp. | −20°C |
Description
Frequently Asked Questions
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Biochem/physiol Actions
Inhibitor of electron transfer at complex III. Induces apoptosis.
Quality
A mixture of antimycins.
Price and Availability
Customers Also Purchased
≥60% oligomycin A basis, ≥90% total oligomycins basis (HPLC)
Documents
Certificate of Analysis
Certificate of Origin
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Safety Information
| Symbol |   GHS06, GHS09 |
| Signal word | Danger |
| Hazard statements | H300-H400 |
| Precautionary statements | P264-P273-P301 + P310 |
| Personal Protective Equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
| Hazard Codes | T |
| Risk Statements | 25 |
| Safety Statements | 26-36/37/39-45 |
| RIDADR | UN 3462 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | CD0350000 |
Technical information & documentation associated with this product is available in the Safety & Documentation tab.
References
Shaham, O., et al., A plasma signature of human mitochondrial disease revealed through metabolic profiling of spent media from cultured muscle cells Proc. Natl. Acad. Sci. U. S. A. 107, 1571-5, (2010) Abstract
Wang, J., et al., Preparative Separation Of Six Antimycin A Components From Antimycin Fermentation Broth By High-speed Counter-current Chromatography. J. Chromatogr. A. 1217, 5687-92, (2010) Abstract
Kruzel, M.L., et al., Lactoferrin Decreases LPS-induced Mitochondrial Dysfunction In Cultured Cells And In Animal Endotoxemia Model. Innate Immunity 16, 67-79, (2010) Abstract
G. Izzo FEBS Lett. 93, 320, (1978)
D. Pietrobon Eur. J. Biochem. 117, 389, (1981)
Tzung, S. P., Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3. Nat. Cell Biol. 3, 183, (2001)
Merck 14,714
Beil. 19,III/IV,4329
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